Science and Innovation

The Pasteur-Fiocruz Center for Immunology and Immunotherapy works in three priority scientific areas: cancer, infectious and neglected diseases, and autoimmune, neurodegenerative and inflammatory diseases.

Research groups and associated projects:

1) Structural computational biology (João Hermínio Martins da Silva Sena).

Associated projects:

- Development of inhibitors for the treatment of neurodegenerative diseases.

- Development of antibody-drug conjugates

2) Antibody and nanobody engineering with therapeutic action (Carla Celedonio, Gilvan Furtado, Marco Medeiros, Piere Lafaye).

Associated projects:

- Development of nanobody/antibody fragments for Neglected Tropical Diseases.

3) Cell and Gene Therapy (Martin Bonamino, Andrea Maranhão, Marcos Lourenzoni, Gilvan Furtado).

Associated projects:

- Development of CAR-T cells

4) Mechanisms of immunological memory (Caroline Passaes).

Associated projects:

- Immunotherapies to improve T-cell function in the fight against infectious diseases.

The aim is for new projects and researchers to address these priority scientific areas. The Center has a dedicated team and works on a multi-user approach, which means that all equipment present is available to all research groups and collaborators involved.